Eco-Friendly Metabolites from Slime Mold Show Potential as Natural Repellents for Root-Knot Nematodes

Japanese researchers have identified 14 organic compounds secreted by the cellular slime mold Dictyostelium discoideum that effectively repel root-knot nematodes (RKNs) without harming soil fertility. These nematodes, known for causing substantial crop losses estimated at nearly USD 173 billion annually, pose a significant challenge in agriculture. Traditional chemical pesticides, while effective, detrimentally affect beneficial soil microorganisms. The study, led by Professor Tamao Saito from Sophia University, utilized novel culturing techniques to isolate these potent compounds, demonstrating their ability to prevent RKN egg hatching and juvenile survival. This breakthrough paves the way for developing environmentally friendly pest control methods, contributing to sustainable agriculture while maintaining soil health. Future research will delve into the mechanisms behind this repellent effect, potentially enhancing the efficacy of integrated pest management strategies.