In a recent study investigating the optical performance of various lighting options for classroom settings, six lamps were evaluated, including two traditional PC lamps and four full-spectrum (PF) lamps. All lamps maintained similar correlated color temperatures and were assessed for desk illuminance and uniformity requirements in accordance with ISO standards. Key ocular parameters, such as ciliary accommodation, modulation transfer function, and high-order aberrations, were measured to gauge visual comfort and fatigue. Results indicated that the PF lamps exhibited significantly lower visual discomfort (VICO) values, particularly PF 2, suggesting enhanced visual quality and reduced fatigue compared to traditional lamps. Additionally, the PF lamps supported better cortical activation and improved melatonin secretion, indicating advantages for maintaining circadian rhythms. Overall, the findings highlight the potential health benefits of utilizing PF lamps in educational environments, with implications for enhancing learning conditions.